Kyle Armbrester

Current Position

Title: Chief Executive Officer Company: Datavant Location: New York (publicly available)

Professional Background

Kyle Armbrester is an accomplished healthcare executive with over two decades of experience transforming healthcare delivery and data infrastructure. He holds both an MBA from Harvard Business School and an AB in Government from Harvard University. His career reflects a consistent focus on modernizing broken healthcare systems through technology, data integration, and value-based care models—moving away from the "facility-centric, break-fix model" that has characterized traditional healthcare delivery.

Armbrester built his career by leading organizations through significant growth phases and strategic transitions. At athenahealth, he served as Chief Product Officer and VP of Strategy & Corporate Development, where he helped grow company revenue from $320 million to $1.2 billion over seven years. During this tenure, he conceived and launched athenahealth's partnership marketplace, building an ecosystem of integrated solutions for healthcare providers. He also founded and successfully sold two healthcare technology companies earlier in his career, demonstrating entrepreneurial capability alongside corporate leadership.

In May 2018, Armbrester joined Signify Health as CEO during a transformational period. He led the company through its Initial Public Offering in February 2021 and orchestrated the acquisition of Caravan Health, significantly expanding Signify's capabilities. Under his leadership, Signify grew to operate a network of over 11,000 clinicians across all 50 states and became the nation's largest home-based care provider. When CVS Health acquired Signify for $8 billion in 2022, Armbrester remained CEO, successfully integrating the company within CVS while maintaining its strategic independence and value-based care focus. In May 2024, he transitioned to his current role as CEO of Datavant, a healthcare data platform company that enables secure, accessible health data sharing across the healthcare ecosystem.

Career Timeline

Education

• MBA, Harvard Business School
• AB in Government, Harvard University

Public Presence

Social Media

Note: Only publicly accessible profiles are documented. No active X/Twitter account for professional healthcare commentary could be verified.

Published Writings

• "COVID-19: 3 Things We Have To Get Right at Re-Entry" — MedCity News (May 2020)
• Various blog posts and articles — Signify Health Blog (2018-2024)
• Industry contributions and perspectives — MedCity News (ongoing)

Public Speaking

• "Building the Largest Health Data Ecosystem in the US" — The Heart of Healthcare Podcast (2024)
• Opening Keynote — Datavant 2024 Conference
• Fireside Chat with Sarah London (Centene CEO) — Future of Health Data Summit (2024)
• Various media interviews and panel discussions on healthcare data, home-based care, and value-based care models

Communication Style

Tone: Strategic, solutions-oriented, pragmatic, and grounded in operational experience. Professional but accessible; often frames technical healthcare problems through their tangible impact on stakeholders.

Recurring themes: Data interoperability and longitudinal patient data as a foundation for better care; modernizing healthcare payment and delivery models away from fee-for-service; value-based care alignment and risk-sharing partnerships; addressing healthcare's administrative waste and inefficiencies; leveraging technology and AI to solve structural healthcare problems; importance of home-based and community care in healthcare delivery.

Notable positions: Strong advocate for moving healthcare away from "facility-centric" models toward home and community-based care; champion of data-driven decision-making across healthcare organizations; proponent of genuine risk-sharing partnerships where providers and payers are financially aligned; believer in the strategic importance of data interoperability as foundational healthcare infrastructure.

Armbrester communicates with confidence rooted in hands-on execution experience. He positions complex healthcare challenges as solvable modernization problems rather than insurmountable obstacles. When discussing healthcare fragmentation and data challenges, he emphasizes how "fixing data flow could reduce administrative waste, improve security, and make care easier for patients and providers alike." His commentary often references market-driven insights and observable healthcare trends (e.g., unsustainable $4 trillion annual spending, shift to home-based care) to ground his strategic arguments. He avoids pure theoretical discussion, instead grounding perspectives in what he has observed while scaling multiple organizations. When announcing acquisitions (Aetion, Apixio divisions), he frames them as responses to specific customer needs and capability gaps rather than abstract growth plays, demonstrating customer-centric decision-making language. His public statements show comfort discussing both business strategy and clinical/operational realities, suggesting he speaks fluently to both investor and healthcare practitioner audiences.

Notable Achievements

• Led Signify Health through successful IPO in February 2021 as a newly public, independent company
• Grew athenahealth revenue from $320 million to $1.2 billion during tenure as CPO and head of corporate development
• Orchestrated acquisition of Caravan Health and integration into Signify's service model
• Successfully transitioned Signify Health through $8 billion CVS Health acquisition while maintaining operational independence
• Built Signify's clinician network to 11,000+ practitioners across all 50 states
• Recognized by Fast Company as part of Signify Health's inclusion in World's Most Innovative Companies (2021)
• Appointed CEO of Datavant with mandate to expand health data ecosystem capabilities
• Led strategic acquisitions at Datavant: Aetion (real-world evidence platform, completed 2025), digital assets from Apixio (2024)
• Currently leading Datavant to 2026 Best in KLAS Award recognition in Risk Adjustment and Outsourced Coding categories
• Founder of two healthcare technology companies (both successfully exited)

Key Relationships

• Board memberships: Datavant (as CEO), Parexel International, Sevita, R1 RCM, Medalogix
• Advisory roles: Founders Workbench Advisory Board (during athenahealth tenure)
• Key investor relationship: New Mountain Capital (primary investor in Datavant)
• Notable peers: Sarah London (CEO, Centene) — publicly engaged in Future of Health Data Summit discussions
• Professional network: 500+ connections on LinkedIn; active engagement across healthcare executive and investor communities