Brigham Hyde

Current Position

Title: Co-Founder & Chief Executive Officer Company: Atropos Health Location: New York (publicly available)

Professional Background

Brigham Hyde is an accomplished healthcare technology entrepreneur and data science leader with 15+ years of experience building businesses at the intersection of real-world evidence, clinical decision support, and artificial intelligence. With a PhD in Clinical Pharmacology from Tufts University School of Medicine and a bachelor's degree in chemistry from Northeastern University, Hyde has consistently focused on democratizing access to high-quality, timely evidence for clinical decision-making. His career trajectory reflects a deep commitment to bridging the "evidence gap"—the reality that approximately 70% of clinical care decisions lack sufficient personalized evidence to guide treatment choices.

Hyde's entrepreneurial journey began at Decision Resources Group, where he served as Chief Data Officer before the company was acquired by Clarivate for $900M in 2020. He subsequently held leadership positions at Eversana, where he established the Data & Analytics business unit as President, and at Symphony AI, where he led investment in and co-founded Concert AI, an oncology real-world data platform that achieved a $1.9B valuation. In August 2022, Hyde became CEO of Atropos Health (founded in late 2020 alongside co-founders Saurabh Gombar and Nigam Shah), securing a $14M Series A led by Breyer Capital. Under his leadership, Atropos has grown to become a leading provider of research-grade real-world evidence at the point of care, culminating in a $33M Series B in 2024 to scale AI-driven evidence generation.

Beyond his executive role, Hyde maintains academic affiliations as research faculty at MIT Media Lab and adjunct faculty at Tufts University School of Medicine, positioning him at the nexus of innovation and evidence-based medicine. His combination of clinical pharmacology expertise, entrepreneurial success, and deep involvement in the real-world evidence ecosystem makes him a distinctive voice in healthcare innovation.

Career Timeline

Education

• Ph.D. in Clinical Pharmacology, Tufts University School of Medicine
• B.S. in Chemistry, Northeastern University

Public Presence

Social Media

Note: Only publicly accessible profiles are documented.

Published Writings

• "Dear Real World (Data) – (Part 1)" — LinkedIn (2023)
• "How AI Can Close the Gap in Evidence-Based Care" — MedCity News (2024)
• "Bridging the Evidence Gap: Brigham Hyde's Mission to Make Data Useful" — The Healthcare Technology Report (2024)
• "Data Is Transforming The Landscape" — PharmaVoice (2021)

Public Speaking & Media Appearances

• PMWC 2026 (Precision Medicine World Conference) — Scheduled speaker (March 4-6, 2026)
• "AI in Healthcare: Top of the First Inning" — AICRisk podcast
• "AI for Founders" podcast — Ryan Estes (December 2025)
• "HealthTech Remedy" podcast — Discussion of AI-driven real-world evidence
• CGTN America interview with Mark Niu — AI in Healthcare and ChatRWD® (September 2025)
• "Real-World Evidence for Healthcare with Brigham Hyde" — Pixel Scientia podcast
• "The RWD & RWE Club Podcast" — Closing the RWE Gap in Medicine (2024)
• HIMSSCast with Andrea Fox (Healthcare IT News) — AI regulation and quality assurance in healthcare
• "Outcomes Rocket" podcast — Transforming Healthcare with Artificial Intelligence (2019)
• "The Future of Clinical Research" — The Futurist Society (interview format)

Communication Style

Tone: Professional, visionary, solution-oriented with pragmatic grounding

Recurring themes: Real-world evidence, evidence gap in healthcare, AI-driven clinical decision support, democratization of evidence, personalized medicine, data infrastructure, regulatory frameworks for healthcare AI

Notable positions: Strong advocate for AI-driven automation of evidence generation; position that infrastructure now exists to bridge the evidence gap; emphasis on federated networks and data privacy/security in evidence generation; belief that evidence should be readily available at point of care for all patients, not just research populations

Hyde communicates as a thoughtful technologist blending clinical credibility with entrepreneurial vision. His writing—exemplified by "Dear Real World (Data)"—balances reflective analysis of healthcare's current limitations with solution-oriented optimism about technological possibilities. He avoids both hyperbole and excessive skepticism, instead grounding arguments in concrete capabilities (ChatRWD®, GENEVA OS™, Atropos Evidence Network) while positioning them as catalysts for systemic change. His vocabulary reflects both clinical precision and accessibility, making technical concepts comprehensible to diverse stakeholder groups (clinicians, researchers, payers, technologists). Across podcast appearances and interviews, he demonstrates consistent messaging around three core themes: (1) the magnitude of the evidence gap problem, (2) the sufficiency of current data infrastructure to solve it, and (3) the role of AI in automating personalized evidence generation. His communication style emphasizes collaboration and partnership—frequently highlighting co-founders and multiple stakeholder groups—rather than singular visionary narrative. This reflects his experience building consensus across healthcare's fragmented ecosystem.

Notable Achievements

• Co-founded and scaled Atropos Health to Series B funding ($33M raised as of 2024) in just 4 years from founding
• Led Concert AI to $1.9B valuation while serving as healthcare partner at Symphony AI
• Established Data & Analytics business at Eversana, building a major revenue driver
• Recognized as Official Member of Forbes Technology Council (2018-2022)
• Served on Global Data Science Advisory Board for Janssen (major pharmaceutical innovator)
• Maintained dual academic appointments at MIT Media Lab and Tufts University School of Medicine while leading Atropos
• Led acquisition integration and data strategy at Decision Resources Group post-Clarivate acquisition ($900M deal)
• Published research on clinical pharmacology, real-world data, and healthcare AI

Key Relationships

• Co-founders of Atropos Health: Saurabh Gombar (Chief Medical Officer), Nigam Shah (Chief Data Scientist, Stanford Health Care)
• Breyer Capital (Series A lead investor relationship)
• Major funders: Emerson Collective, Boston Millennia Partners, Presidio Ventures, Samsung Next, Audere Capital
• Academic collaborators: MIT Media Lab faculty, Tufts University School of Medicine
• Industry affiliations: Forbes Technology Council (former), Janssen Global Data Science Advisory Board (former), AI assurance labs development partnerships
• Venture capital: Audere Capital (Venture Partner relationship)